3CA7

High Resolution Crystal Structure of the EGF domain of Spitz

3CA7 の概要

• エントリーDOI: 10.2210/pdb3ca7/pdb
• 分子名称: Protein spitz (2 entities in total)
• 機能のキーワード: spitz, argos, egf, developmental protein, differentiation, egf-like domain, endoplasmic reticulum, glycoprotein, golgi apparatus, membrane, neurogenesis, transmembrane, hormone-signaling protein complex, hormone/signaling protein
• 由来する生物種: Drosophila melanogaster (Fruit fly)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: Q01083
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 6012.86

構造登録者

Klein, D.E.,Stayrook, S.E.,Lemmon, M.A. (登録日: 2008-02-19, 公開日: 2008-05-20, 最終更新日: 2023-08-30)

• 主引用文献: Klein, D.E.,Stayrook, S.E.,Shi, F.,Narayan, K.,Lemmon, M.A.; Structural basis for EGFR ligand sequestration by Argos.; Nature, 453:1271-1275, 2008; PubMed: 18500331; DOI: 10.1038/nature06978

実験手法

X-RAY DIFFRACTION (1.5 Å)