3C9E

Crystal structure of the cathepsin K : chondroitin sulfate complex.

3C9E の概要

• エントリーDOI: 10.2210/pdb3c9e/pdb
• 分子名称: Cathepsin K, 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose-(1-4)-beta-D-glucopyranuronic acid, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: n:1 cathepsin k : chondroitin sulfate complex, "beads-on-a-string" organization, hydrolase, lysosome, protease, thiol protease
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Lysosome: P43235
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25320.14

構造登録者

Kienetz, M.,Cherney, M.M.,James, M.N.G.,Bromme, D. (登録日: 2008-02-15, 公開日: 2008-08-26, 最終更新日: 2020-07-29)

• 主引用文献: Li, Z.,Kienetz, M.,Cherney, M.M.,James, M.N.,Bromme, D.; The crystal and molecular structures of a cathepsin K:chondroitin sulfate complex.; J.Mol.Biol., 383:78-91, 2008; PubMed: 18692071; DOI: 10.1016/j.jmb.2008.07.038

実験手法

X-RAY DIFFRACTION (1.8 Å)