3C5L

Polo-like kinase 1 Polo box domain in complex with PPHSpT peptide

Summary for 3C5L

Entry DOI	10.2210/pdb3c5l/pdb
Descriptor	Serine/threonine-protein kinase PLK1, Peptide (3 entities in total)
Functional Keywords	plk1, polo-like kinase 1, polo box domain, phosphopeptide, atp-binding, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase
Biological source	Homo sapiens (Human)
Cellular location	Nucleus: P53350
Total number of polymer chains	2
Total formula weight	26213.78
Authors	Lim, D.C.,Yaffe, M.B. (deposition date: 2008-01-31, release date: 2009-02-17, Last modification date: 2023-08-30)
Primary citation	Yun, S.M.,Moulaei, T.,Lim, D.,Bang, J.K.,Park, J.E.,Shenoy, S.R.,Liu, F.,Kang, Y.H.,Liao, C.,Soung, N.K.,Lee, S.,Yoon, D.Y.,Lim, Y.,Lee, D.H.,Otaka, A.,Appella, E.,McMahon, J.B.,Nicklaus, M.C.,Burke, T.R.,Yaffe, M.B.,Wlodawer, A.,Lee, K.S. Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1. Nat.Struct.Mol.Biol., 16:876-882, 2009 Cited by PubMed: 19597481 DOI: 10.1038/nsmb.1628 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.33 Å)

Structure validation