3C58

Crystal structure of a complex between the wild-type lactococcus lactis Fpg (MutM) and a N7-Benzyl-Fapy-dG containing DNA

3C58 の概要

• エントリーDOI: 10.2210/pdb3c58/pdb
• 分子名称: DNA (5'-D(*DGP*DCP*DGP*DAP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DCP*DTP*DCP*DTP*DTP*DTP*(SOS)P*DTP*DTP*DTP*DCP*DTP*DCP*DG)-3'), DNA glycosylase, ... (6 entities in total)
• 機能のキーワード: protein-dna complex, glycosylase, benzyl-fapy, dna repair, hydrolase-dna complex, dna damage, dna-binding, glycosidase, lyase, metal-binding, multifunctional enzyme, zinc-finger, hydrolase/dna
• 由来する生物種: Lactococcus lactis; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 39939.49

構造登録者

Coste, F.,Castaing, B.,Carell, T. (登録日: 2008-01-31, 公開日: 2008-12-16, 最終更新日: 2023-11-01)

• 主引用文献: Coste, F.,Ober, M.,Le Bihan, Y.V.,Izquierdo, M.A.,Hervouet, N.,Mueller, H.,Carell, T.,Castaing, B.; Bacterial base excision repair enzyme Fpg recognizes bulky N7-substituted-FapydG lesion via unproductive binding mode; Chem.Biol., 15:706-717, 2008; PubMed: 18635007; DOI: 10.1016/j.chembiol.2008.05.014

実験手法

X-RAY DIFFRACTION (1.9 Å)