3C52
Class II fructose-1,6-bisphosphate aldolase from helicobacter pylori in complex with phosphoglycolohydroxamic acid, a competitive inhibitor
Summary for 3C52
Entry DOI | 10.2210/pdb3c52/pdb |
Related | 3C3S 3C56 |
Descriptor | Fructose-bisphosphate aldolase, ZINC ION, CALCIUM ION, ... (6 entities in total) |
Functional Keywords | class ii, fbp, aldolase, glycolysis, inhibitor, phosphoglycolohydroxamic acid, lyase, metal-binding |
Biological source | Helicobacter pylori |
Total number of polymer chains | 2 |
Total formula weight | 68200.67 |
Authors | Coincon, M.,Sygusch, J. (deposition date: 2008-01-30, release date: 2008-08-26, Last modification date: 2024-04-03) |
Primary citation | Fonvielle, M.,Coincon, M.,Daher, R.,Desbenoit, N.,Kosieradzka, K.,Barilone, N.,Gicquel, B.,Sygusch, J.,Jackson, M.,Therisod, M. Synthesis and Biochemical Evaluation of Selective Inhibitors of Class II Fructose Bisphosphate Aldolases: Towards New Synthetic Antibiotics. Chemistry, 14:8521-8529, 2008 Cited by PubMed: 18688832DOI: 10.1002/chem.200800857 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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