3C13
Low pH-value crystal structure of emodin in complex with the catalytic subunit of protein kinase CK2
Summary for 3C13
Entry DOI | 10.2210/pdb3c13/pdb |
Related | 1F0Q 1JWH 1LP4 1PJK 2PVR 2RKP 3BQC |
Descriptor | Casein kinase II subunit alpha, CHLORIDE ION, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ... (4 entities in total) |
Functional Keywords | protein kinase ck2, casein kinase 2, eukaryotic protein kinases, emodin, atp-competitive inhibitor, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase, wnt signaling pathway |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus : P68400 |
Total number of polymer chains | 1 |
Total formula weight | 40407.89 |
Authors | Niefind, K.,Raaf, J.,Issinger, O.-G. (deposition date: 2008-01-22, release date: 2008-02-12, Last modification date: 2023-11-01) |
Primary citation | Raaf, J.,Klopffleisch, K.,Issinger, O.-G.,Niefind, K. The Catalytic Subunit of Human Protein Kinase CK2 Structurally Deviates from Its Maize Homologue in Complex with the Nucleotide Competitive Inhibitor Emodin J.Mol.Biol., 377:1-8, 2008 Cited by PubMed: 18242640DOI: 10.1016/j.jmb.2008.01.008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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