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3BXS

Crystal Structures Of Highly Constrained Substrate And Hydrolysis Products Bound To HIV-1 Protease. Implications For Catalytic Mechanism

3BXS の概要
エントリーDOI10.2210/pdb3bxs/pdb
関連するPDBエントリー1B6P
分子名称Protease, SULFATE ION, (9S,12S)-9-(1-methylethyl)-7,10-dioxo-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-1(16),14,17-triene-12-carboxylic acid, ... (4 entities in total)
機能のキーワードhiv protease, hivpr, substrate, product, aids, aspartyl protease, capsid maturation, core protein, cytoplasm, dna integration, dna recombination, dna-directed dna polymerase, endonuclease, hydrolase, lipoprotein, magnesium, membrane, metal-binding, multifunctional enzyme, myristate, nuclease, nucleotidyltransferase, nucleus, phosphoprotein, rna-binding, rna-directed dna polymerase, transferase, viral nucleoprotein, virion, zinc, zinc-finger
細胞内の位置Gag-Pol polyprotein: Host cell membrane; Lipid-anchor. Matrix protein p17: Virion membrane; Lipid- anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion . Reverse transcriptase/ribonuclease H: Virion . Integrase: Virion : P03369
タンパク質・核酸の鎖数2
化学式量合計22544.40
構造登録者
Tyndall, J.D.,Pattenden, L.K.,Reid, R.C.,Hu, S.H.,Alewood, D.,Alewood, P.F.,Walsh, T.,Fairlie, D.P.,Martin, J.L. (登録日: 2008-01-14, 公開日: 2008-03-25, 最終更新日: 2023-11-15)
主引用文献Tyndall, J.D.,Pattenden, L.K.,Reid, R.C.,Hu, S.H.,Alewood, D.,Alewood, P.F.,Walsh, T.,Fairlie, D.P.,Martin, J.L.
Crystal Structures of Highly Constrained Substrate and Hydrolysis Products Bound to HIV-1 Protease. Implications for the Catalytic Mechanism
Biochemistry, 47:3736-3744, 2008
Cited by
PubMed: 18311928
DOI: 10.1021/bi7023157
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (1.6 Å)
構造検証レポート
Validation report summary of 3bxs
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-03-27に公開中

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