3BXN
The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA
Summary for 3BXN
Entry DOI | 10.2210/pdb3bxn/pdb |
Related | 3BVN |
Descriptor | HLA-B*1402 extracellular domain, beta-2-microglobulin, Cathepsin A signal sequence octapeptide, ... (5 entities in total) |
Functional Keywords | major histocompatibility complex, mhc, human leokocyte antigen, hla, hla-b14, hla-b*1402, hla-b1402, hla-b*14, pcata, cathepsin a, ankylosing spondylitis, autoimmunity, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P61769 Lysosome: P10619 |
Total number of polymer chains | 3 |
Total formula weight | 45402.28 |
Authors | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (deposition date: 2008-01-14, release date: 2009-02-03, Last modification date: 2023-08-30) |
Primary citation | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A. Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284:29784-29797, 2009 Cited by PubMed: 19617632DOI: 10.1074/jbc.M109.038497 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.864 Å) |
Structure validation
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