3BXN

The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA

3BXN の概要

• エントリーDOI: 10.2210/pdb3bxn/pdb
• 関連するPDBエントリー: 3BVN
• 分子名称: HLA-B*1402 extracellular domain, beta-2-microglobulin, Cathepsin A signal sequence octapeptide, ... (5 entities in total)
• 機能のキーワード: major histocompatibility complex, mhc, human leokocyte antigen, hla, hla-b14, hla-b*1402, hla-b1402, hla-b*14, pcata, cathepsin a, ankylosing spondylitis, autoimmunity, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted: P61769; Lysosome: P10619
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45402.28

構造登録者

Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (登録日: 2008-01-14, 公開日: 2009-02-03, 最終更新日: 2023-08-30)

• 主引用文献: Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A.; Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens; J.Biol.Chem., 284:29784-29797, 2009; PubMed: 19617632; DOI: 10.1074/jbc.M109.038497

実験手法

X-RAY DIFFRACTION (1.864 Å)