3BXN

The high resolution crystal structure of HLA-B*1402 complexed with a Cathepsin A signal sequence peptide, pCatA

3BXN の概要

関連するPDBエントリー3BVN
分子名称HLA-B*1402 extracellular domain, beta-2-microglobulin, Cathepsin A signal sequence octapeptide, ... (5 entities in total)
機能のキーワードmajor histocompatibility complex, mhc, human leokocyte antigen, hla, hla-b14, hla-b*1402, hla-b1402, hla-b*14, pcata, cathepsin a, ankylosing spondylitis, autoimmunity, immune system
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Secreted P61769
Lysosome P10619
ポリマー鎖数3
分子量合計45402.28
構造登録者
Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (登録日: 2008-01-14, 公開日: 2009-02-03, 最終更新日: 2011-07-13)
主引用文献
Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A.
Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284:29784-29797, 2009
PubMed: 19617632 (主引用文献が同じPDBエントリー)
DOI: 10.1074/jbc.M109.038497
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.864 Å)
NMR情報
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.219504.2%1.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード