3BVN
High resolution crystal structure of HLA-B*1402 in complex with the latent membrane protein 2 peptide (LMP2) of Epstein-Barr virus
3BVN の概要
エントリーDOI | 10.2210/pdb3bvn/pdb |
関連するPDBエントリー | 1UXS |
分子名称 | HLA class I histocompatibility antigen, B*1402 alpha chain, Beta-2-microglobulin, Latent membrane protein 2 peptide, ... (4 entities in total) |
機能のキーワード | major histocompatibility complex, mhc, human leukocyte antigen, hla, hla-b14, hla-b*14, hla-b1402, hla-b*1402, plmp2, ankylosing spondylitis, disease mutation, glycation, glycoprotein, immune response, immunoglobulin domain, mhc i, pyrrolidone carboxylic acid, secreted, alternative splicing, cytoplasm, host-virus interaction, membrane, phosphoprotein, transmembrane, ubl conjugation, immune system |
由来する生物種 | Homo sapiens (Human) 詳細 |
細胞内の位置 | Secreted: P61769 Isoform LMP2A: Host cell membrane; Multi- pass membrane protein. Isoform LMP2B: Host endomembrane system; Multi-pass membrane protein: P13285 |
タンパク質・核酸の鎖数 | 6 |
化学式量合計 | 90710.59 |
構造登録者 | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Uchanska-Ziegler, B.,Ziegler, A. (登録日: 2008-01-07, 公開日: 2009-02-03, 最終更新日: 2023-08-30) |
主引用文献 | Kumar, P.,Vahedi-Faridi, A.,Saenger, W.,Merino, E.,Lopez de Castro, J.A.,Uchanska-Ziegler, B.,Ziegler, A. Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens J.Biol.Chem., 284:29784-29797, 2009 Cited by PubMed: 19617632DOI: 10.1074/jbc.M109.038497 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.55 Å) |
構造検証レポート
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