3BSN

Norwalk Virus polymerase bound to 5-nitrocytidine triphosphate and primer-template RNA

3BSN の概要

• エントリーDOI: 10.2210/pdb3bsn/pdb
• 関連するPDBエントリー: 1SH0 3BSO
• 分子名称: RNA dependent RNA polymerase, RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*G)-3'), RNA (5'-R(*UP*GP*CP*CP*CP*GP*GP*GP*(N5M))-3'), ... (7 entities in total)
• 機能のキーワード: rna-dependent rna polymerase, viral replication, antiviral enzyme inhibitor, helicase, hydrolase, nucleotide-binding, nucleotidyltransferase, rna replication, rna-directed rna polymerase, transferase, transferase-rna complex, transferase/rna
• 由来する生物種: Norwalk virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 63370.25

構造登録者

Zamyatkin, D.F.,Ng, K.K.S. (登録日: 2007-12-26, 公開日: 2008-01-08, 最終更新日: 2023-08-30)

• 主引用文献: Zamyatkin, D.F.,Parra, F.,Alonso, J.M.,Harki, D.A.,Peterson, B.R.,Grochulski, P.,Ng, K.K.; Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.; J.Biol.Chem., 283:7705-7712, 2008; PubMed: 18184655; DOI: 10.1074/jbc.M709563200

実験手法

X-RAY DIFFRACTION (1.8 Å)