3BQC

High pH-value crystal structure of emodin in complex with the catalytic subunit of protein kinase CK2

3BQC の概要

• エントリーDOI: 10.2210/pdb3bqc/pdb
• 関連するPDBエントリー: 1F0Q 1JWH 2PVR 2RKP
• 分子名称: Casein kinase II subunit alpha, CHLORIDE ION, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ... (4 entities in total)
• 機能のキーワード: protein kinase ck2, casein kinase 2, eukaryotic protein kinases, emodin, atp-competitive inhibitor, atp-binding, nucleotide-binding, serine/threonine-protein kinase, transferase, wnt signaling pathway
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40407.89

構造登録者

Niefind, K.,Raaf, J.,Issinger, O.-G. (登録日: 2007-12-20, 公開日: 2008-01-15, 最終更新日: 2023-11-01)

• 主引用文献: Raaf, J.,Klopffleisch, K.,Issinger, O.-G.,Niefind, K.; The Catalytic Subunit of Human Protein Kinase CK2 Structurally Deviates from Its Maize Homologue in Complex with the Nucleotide Competitive Inhibitor Emodin; J.Mol.Biol., 377:1-8, 2008; PubMed: 18242640; DOI: 10.1016/j.jmb.2008.01.008

実験手法

X-RAY DIFFRACTION (1.5 Å)