3BM5

Crystal structure of O-acetyl-serine sulfhydrylase from Entamoeba histolytica in complex with cysteine

Summary for 3BM5

• Entry DOI: 10.2210/pdb3bm5/pdb
• Related: 2PQM
• Descriptor: Cysteine synthase, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (5 entities in total)
• Functional Keywords: cysteine synthase, cys-oass complex, domain movement, pyridoxal phosphate, lyase, lyase-biosynthetic protein complex, lyase/biosynthetic protein
• Biological source: Entamoeba histolytica HM-1:IMSS
• Total number of polymer chains: 2
• Total formula weight: 75022.99

Authors

Krishna, C.,Kumar, M.,Kumar, S.,Gourinath, S. (deposition date: 2007-12-12, release date: 2008-04-01, Last modification date: 2023-11-01)

• Primary citation: Chinthalapudi, K.,Kumar, M.,Kumar, S.,Jain, S.,Alam, N.,Gourinath, S.; Crystal structure of native O-acetyl-serine sulfhydrylase from Entamoeba histolytica and its complex with cysteine: structural evidence for cysteine binding and lack of interactions with serine acetyl transferase.; Proteins, 72:1222-1232, 2008; PubMed: 18350570; DOI: 10.1002/prot.22013

Experimental method

X-RAY DIFFRACTION (2.4 Å)