3BL2

Crystal Structure of M11, the BCL-2 Homolog of Murine Gamma-herpesvirus 68, Complexed with Mouse Beclin1 (residues 106-124)

3BL2 の概要

• エントリーDOI: 10.2210/pdb3bl2/pdb
• 分子名称: V-bcl-2, Beclin-1 (3 entities in total)
• 機能のキーワード: protein-protein complex, viral bcl-2, beclin1, apoptosis, m11, autophagy, antiviral defense, coiled coil, cytoplasm, golgi apparatus, membrane, viral protein-apoptosis complex, viral protein/apoptosis
• 由来する生物種: Murid herpesvirus 4 (Murine herpesvirus 68); 詳細
• 細胞内の位置: Cytoplasm . Beclin-1-C 35 kDa: Mitochondrion . Beclin-1-C 37 kDa: Mitochondrion : O88597
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 34789.75

構造登録者

Oh, B.-H.,Woo, J.-S.,Ku, B. (登録日: 2007-12-10, 公開日: 2008-02-12, 最終更新日: 2023-11-01)

• 主引用文献: Ku, B.,Woo, J.-S.,Liang, C.,Lee, K.-H.,Hong, H.-S.,E, X.,Kim, K.-S.,Jung, J.U.,Oh, B.-H.; Structural and Biochemical Bases for the Inhibition of Autophagy and Apoptosis by Viral BCL-2 of Murine gamma-Herpesvirus 68; Plos Pathog., 4:e25-e25, 2008; PubMed: 18248095; DOI: 10.1371/journal.ppat.0040025

実験手法

X-RAY DIFFRACTION (2.3 Å)