3BKY

Crystal Structure of Chimeric Antibody C2H7 Fab in complex with a CD20 Peptide

3BKY の概要

分子名称the Fab fragment of chimeric 2H7, heavy chain, the Fab fragment of chimeric 2H7, light chain, B-lymphocyte antigen CD20, ... (4 entities in total)
機能のキーワード2h7, c2h7, chimeric antibody, fab, cd20, fab-peptide complex, b-cell activation, membrane, phosphoprotein, transmembrane, immune system
由来する生物種Homo sapiens, Mus musculus (human, house mouse)
詳細
細胞内の位置Cell membrane ; Multi-pass membrane protein  P11836
ポリマー鎖数3
分子量合計50212.83
構造登録者
Du, J.,Zhong, C.,Ding, J. (登録日: 2007-12-07, 公開日: 2008-04-29, 最終更新日: 2017-10-25)
主引用文献
Du, J.,Wang, H.,Zhong, C.,Peng, B.,Zhang, M.,Li, B.,Hou, S.,Guo, Y.,Ding, J.
Crystal structure of chimeric antibody C2H7 Fab in complex with a CD20 peptide
Mol.Immunol., 45:2861-2868, 2008
PubMed: 18346788 (主引用文献が同じPDBエントリー)
DOI: 10.1016/j.molimm.2008.01.034
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.61 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.244131.6%10.5%14.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード