3BCN
Crystal structure of a papain-like cysteine protease Ervatamin-A complexed with irreversible inhibitor E-64
Replaces: 2PSCSummary for 3BCN
Entry DOI | 10.2210/pdb3bcn/pdb |
Descriptor | Ervatamin-A, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, BETA-MERCAPTOETHANOL, ... (4 entities in total) |
Functional Keywords | protease-inhibitor complex, papain-like fold, plant cysteine protease, ervatamin, hydrolase, thiol protease |
Biological source | Tabernaemontana divaricata |
Total number of polymer chains | 2 |
Total formula weight | 46505.28 |
Authors | Ghosh, R.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S. (deposition date: 2007-11-13, release date: 2007-11-27, Last modification date: 2023-11-01) |
Primary citation | Ghosh, R.,Chakraborty, S.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S. Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria Febs J., 275:421-434, 2008 Cited by PubMed: 18167146DOI: 10.1111/j.1742-4658.2007.06211.x PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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