3BCN

Crystal structure of a papain-like cysteine protease Ervatamin-A complexed with irreversible inhibitor E-64

「2PSC」から置き換えられました

3BCN の概要

• エントリーDOI: 10.2210/pdb3bcn/pdb
• 分子名称: Ervatamin-A, N-[N-[1-HYDROXYCARBOXYETHYL-CARBONYL]LEUCYLAMINO-BUTYL]-GUANIDINE, BETA-MERCAPTOETHANOL, ... (4 entities in total)
• 機能のキーワード: protease-inhibitor complex, papain-like fold, plant cysteine protease, ervatamin, hydrolase, thiol protease
• 由来する生物種: Tabernaemontana divaricata
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 46505.28

構造登録者

Ghosh, R.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S. (登録日: 2007-11-13, 公開日: 2007-11-27, 最終更新日: 2023-11-01)

• 主引用文献: Ghosh, R.,Chakraborty, S.,Chakrabarti, C.,Dattagupta, J.K.,Biswas, S.; Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria; Febs J., 275:421-434, 2008; PubMed: 18167146; DOI: 10.1111/j.1742-4658.2007.06211.x

実験手法

X-RAY DIFFRACTION (2.85 Å)