3B96

Structural Basis for Substrate Fatty-Acyl Chain Specificity: Crystal Structure of Human Very-Long-Chain Acyl-CoA Dehydrogenase

3B96 の概要

• エントリーDOI: 10.2210/pdb3b96/pdb
• 分子名称: Very long-chain specific acyl-CoA dehydrogenase, TETRADECANOYL-COA, FLAVIN-ADENINE DINUCLEOTIDE, ... (4 entities in total)
• 機能のキーワード: acyl-coa, fatty acid beta-oxidation, dehydrogenase, very long chain, mitochondria, membrane, acetylation, alternative splicing, cardiomyopathy, disease mutation, fad, fatty acid metabolism, flavoprotein, lipid metabolism, mitochondrion, oxidoreductase, polymorphism, transit peptide, ubl conjugation
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Mitochondrion inner membrane: P49748
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 65223.31

構造登録者

McAndrew, R.P.,Wang, Y.,Mohsen, A.W.,He, M.,Vockley, J.,Kim, J.J. (登録日: 2007-11-02, 公開日: 2008-02-12, 最終更新日: 2024-02-21)

• 主引用文献: McAndrew, R.P.,Wang, Y.,Mohsen, A.W.,He, M.,Vockley, J.,Kim, J.J.; Structural basis for substrate fatty acyl chain specificity: crystal structure of human very-long-chain acyl-CoA dehydrogenase.; J.Biol.Chem., 283:9435-9443, 2008; PubMed: 18227065; DOI: 10.1074/jbc.M709135200

実験手法

X-RAY DIFFRACTION (1.91 Å)