Crystal structure of a synaptic adhesion complex

Summary for 3B3Q

DescriptorNlgn1 protein, NRXN1 protein, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordssynaptic formation, adhesion, heterophilic, protein-protein complex, calcium binding, membrane, transmembrane, cell adhesion
Biological sourceMus musculus (house mouse)
Total number of polymer chains4
Total molecular weight173791.22
Chen, X.,Liu, H.,Shim, A.,Focia, P.,He, X. (deposition date: 2007-10-22, release date: 2008-01-15, Last modification date: 2013-05-15)
Primary citation
Chen, X.,Liu, H.,Shim, A.H.,Focia, P.J.,He, X.
Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.
Nat.Struct.Mol.Biol., 15:50-56, 2008
PubMed: 18084303 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1350
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.262201.3%8.4%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report