3B3I

Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes

3B3I の概要

• エントリーDOI: 10.2210/pdb3b3i/pdb
• 関連するPDBエントリー: 1OF2 1OGT
• 分子名称: HLA class I histocompatibility antigen, B-27 alpha chain, Beta-2-microglobulin, Vasoactive intestinal polypeptide receptor 1, ... (5 entities in total)
• 機能のキーワード: hla-b2709, ankylosing spondylitis, glycoprotein, host-virus interaction, immune response, membrane, mhc i, transmembrane, disease mutation, glycation, immunoglobulin domain, pyrrolidone carboxylic acid, secreted, g-protein coupled receptor, phosphorylation, receptor, transducer, protein binding, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P03989; Secreted . Note=(Microbial infection) In the presence of M: P61769; Cell membrane; Multi-pass membrane protein: P32241
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 45782.81

構造登録者

Beltrami, A.,Rossmann, M.,Fiorillo, M.T.,Paladini, F.,Sorrentino, R.,Saenger, W.,Kumar, P.,Ziegler, A.,Uchanska-Ziegler, B. (登録日: 2007-10-22, 公開日: 2008-07-22, 最終更新日: 2023-11-15)

• 主引用文献: Beltrami, A.,Rossmann, M.,Fiorillo, M.T.,Paladini, F.,Sorrentino, R.,Saenger, W.,Kumar, P.,Ziegler, A.,Uchanska-Ziegler, B.; Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes.; J.Biol.Chem., 283:27189-27199, 2008; PubMed: 18650441; DOI: 10.1074/jbc.M802818200

実験手法

X-RAY DIFFRACTION (1.86 Å)