3AUV
Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface
Summary for 3AUV
Entry DOI | 10.2210/pdb3auv/pdb |
Descriptor | sc-dsFv derived from the G6-Fab (2 entities in total) |
Functional Keywords | sc-dsfv (disulfide-stabilized scfv), scfv, monovalent antibody, vegf, antibody engineering, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 174938.09 |
Authors | Yu, C.M.,Peng, H.P.,Chen, I.C.,Lee, Y.C.,Chen, J.B.,Tsai, K.C.,Chen, C.T.,Chang, J.Y.,Yang, E.W.,Hsu, P.C.,Jian, J.W.,Hsu, H.J.,Chang, H.J.,Hsu, W.L.,Huang, K.F.,Ma, A.C.,Yang, A.S. (deposition date: 2011-02-16, release date: 2012-02-22, Last modification date: 2012-04-25) |
Primary citation | Yu, C.M.,Peng, H.P.,Chen, I.C.,Lee, Y.C.,Chen, J.B.,Tsai, K.C.,Chen, C.T.,Chang, J.Y.,Yang, E.W.,Hsu, P.C.,Jian, J.W.,Hsu, H.J.,Chang, H.J.,Hsu, W.L.,Huang, K.F.,Ma, A.C.,Yang, A.S. Rationalization and design of the complementarity determining region sequences in an antibody-antigen recognition interface Plos One, 7:e33340-e33340, 2012 Cited by PubMed: 22457753DOI: 10.1371/journal.pone.0033340 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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