3AOW

Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with AKG

3AOW の概要

• エントリーDOI: 10.2210/pdb3aow/pdb
• 関連するPDBエントリー: 3AOV
• 分子名称: Putative uncharacterized protein PH0207, PYRIDOXAL-5'-PHOSPHATE, 2-OXOGLUTARIC ACID, ... (4 entities in total)
• 機能のキーワード: protein-plp-akg triple complex, schiff-base linkage, kynurenine aminotransferase, cofactor and substrate complex, aminotransferase, plp binding, transamination, transferase
• 由来する生物種: Pyrococcus horikoshii
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 103112.28

構造登録者

Okada, K.,Angkawidjaja, C.,Koga, Y.,Takano, K.,Kanaya, S. (登録日: 2010-10-07, 公開日: 2011-10-12, 最終更新日: 2023-11-01)

• 主引用文献: Okada, K.,Angkawidjaja, C.,Koga, Y.,Takano, K.,Kanaya, Y.; Characterization of kynurenine aminotransferase from hyperthermophilic archaeon: enzymatic activity for conversion to kynurenic acid is allosterically regulated by alpha-ketoglutaric acid cooperatively with kynurenine; To be Published,

実験手法

X-RAY DIFFRACTION (1.56 Å)