3AK9

Crystal structure of the SEp22 dodecamer, a Dps-like protein from Salmonella enterica subsp. enterica serovar Enteritidis, FE-soaked form

3AK9 の概要

• エントリーDOI: 10.2210/pdb3ak9/pdb
• 関連するPDBエントリー: 3AK8
• 分子名称: DNA protection during starvation protein, FE (II) ION, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: dps-like protein, dodecamer, iron-binding protein, metal binding protein, oxidoreductase
• 由来する生物種: Salmonella enterica subsp. enterica serovar Kentucky
• 細胞内の位置: Cytoplasm (By similarity): B3YEF4
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 226250.79

構造登録者

Miyamoto, T.,Asahina, Y.,Miyazaki, S.,Shimizu, H.,Ohto, U.,Noguchi, S.,Satow, Y. (登録日: 2010-07-08, 公開日: 2011-01-12, 最終更新日: 2023-11-01)

主引用文献

Miyamoto, T.,Asahina, Y.,Miyazaki, S.,Shimizu, H.,Ohto, U.,Noguchi, S.,Satow, Y.
Structures of the SEp22 dodecamer, a Dps-like protein from Salmonella enterica subsp. enterica serovar Enteritidis
Acta Crystallogr.,Sect.F, 67:17-22, 2011

PubMed Abstract: The crystal structure of SEp22, a DNA-binding protein from starved cells from Salmonella enterica subsp. enterica serovar Enteritidis, has been determined in two forms: the native state at 1.25 Å resolution and an iron-soaked form at 1.30 Å resolution. The SEp22 protomers form a dodecameric shell with 23 symmetry and a single iron ion per protomer was found at the ferroxidase centre in the iron-soaked form. Along the threefold axes of the 23 symmetry, hydrophilic Asp channels that consist of Asp146 were found. Iron ions may flow into the cavity of the dodecameric shell through the Asp channels.

PubMed: 21206015
DOI: 10.1107/S1744309110043113

実験手法

X-RAY DIFFRACTION (1.3 Å)