3AGV

Crystal structure of a human IgG-aptamer complex

Summary for 3AGV

• Entry DOI: 10.2210/pdb3agv/pdb
• Descriptor: Ig gamma-1 chain C region, 5'-R(*GP*GP*AP*GP*GP*(UFT)P*GP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*GP*AP*AP*A*GP*GP*AP*AP*(CFZ)P*(UFT)P*(CFZ)P*(CFZ)P*A)-3', alpha-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, ... (6 entities in total)
• Functional Keywords: igg, rna aptamer, immune system-rna complex, immune system/rna
• Biological source: Homo sapiens (human)
• Cellular location: Secreted: P01857
• Total number of polymer chains: 4
• Total formula weight: 65623.40

Authors

Nomura, Y.,Sugiyama, S.,Sakamoto, T.,Miyakawa, S.,Adachi, H.,Takano, K.,Murakami, S.,Inoue, T.,Mori, Y.,Nakamura, Y.,Matsumura, H. (deposition date: 2010-04-08, release date: 2010-11-10, Last modification date: 2023-11-01)

• Primary citation: Nomura, Y.,Sugiyama, S.,Sakamoto, T.,Miyakawa, S.,Adachi, H.,Takano, K.,Murakami, S.,Inoue, T.,Mori, Y.,Nakamura, Y.,Matsumura, H.; Conformational plasticity of RNA for target recognition as revealed by the 2.15 A crystal structure of a human IgG-aptamer complex; Nucleic Acids Res., 38:7822-7829, 2010; PubMed: 20675355; DOI: 10.1093/nar/gkq615

Experimental method

X-RAY DIFFRACTION (2.15 Å)