3AFA

The human nucleosome structure

Summary for 3AFA

Entry DOI	10.2210/pdb3afa/pdb
Descriptor	Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (8 entities in total)
Functional Keywords	histone-fold, dna-binding protein, chromosomal protein, citrullination, dna-binding, methylation, nucleosome core, nucleus, phosphoprotein, isopeptide bond, antibiotic, antimicrobial, structural protein-dna complex, structural protein/dna
Biological source	Homo sapiens (human) More
Cellular location	Nucleus: P68431 P62805 P04908 P06899
Total number of polymer chains	10
Total formula weight	202812.00
Authors	Tachiwana, H.,Kagawa, W.,Osakabe, A.,Koichiro, K.,Shiga, T.,Kimura, H.,Kurumizaka, H. (deposition date: 2010-02-24, release date: 2010-05-26, Last modification date: 2023-11-01)
Primary citation	Tachiwana, H.,Kagawa, W.,Osakabe, A.,Kawaguchi, K.,Shiga, T.,Hayashi-Takanaka, Y.,Kimura, H.,Kurumizaka, H. Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T Proc.Natl.Acad.Sci.USA, 107:10454-10459, 2010 Cited by PubMed: 20498094 DOI: 10.1073/pnas.1003064107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation