3AF4

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GMPPCP

Summary for 3AF4

Entry DOI	10.2210/pdb3af4/pdb
Related	2ZS8 2ZS9 2ZSA 2ZSB 2ZSE 2ZSF 3AEZ 3AF0 3AF1 3AF2 3AF3
Descriptor	Pantothenate kinase, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, GLYCEROL, ... (4 entities in total)
Functional Keywords	transferase, homodimer, coa biosynthesis, nucleotide binding, atp-binding, kinase, nucleotide-binding
Biological source	Mycobacterium tuberculosis
Cellular location	Cytoplasm (By similarity): P63810
Total number of polymer chains	1
Total formula weight	37423.28
Authors	Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M. (deposition date: 2010-02-22, release date: 2010-05-26, Last modification date: 2023-11-01)
Primary citation	Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M. M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations J.Mol.Biol., 400:171-185, 2010 Cited by PubMed: 20451532 DOI: 10.1016/j.jmb.2010.04.064 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation