3AEZ

Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with GDP and Phosphopantothenate

3AEZ の概要

• エントリーDOI: 10.2210/pdb3aez/pdb
• 関連するPDBエントリー: 2ZS8 2ZS9 2ZSA 2ZSB 2ZSE 2ZSF 3AF0 3AF1 3AF2 3AF3 3AF4
• 分子名称: Pantothenate kinase, GUANOSINE-5'-DIPHOSPHATE, N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanine, ... (6 entities in total)
• 機能のキーワード: transferase, homodimer, coa biosynthesis, nucleotide binding, atp-binding, kinase, nucleotide-binding
• 由来する生物種: Mycobacterium tuberculosis
• 細胞内の位置: Cytoplasm (By similarity): P63810
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37667.48

構造登録者

Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M. (登録日: 2010-02-18, 公開日: 2010-05-26, 最終更新日: 2023-11-01)

• 主引用文献: Chetnani, B.,Kumar, P.,Surolia, A.,Vijayan, M.; M. tuberculosis pantothenate kinase: dual substrate specificity and unusual changes in ligand locations; J.Mol.Biol., 400:171-185, 2010; PubMed: 20451532; DOI: 10.1016/j.jmb.2010.04.064

実験手法

X-RAY DIFFRACTION (2.2 Å)