3AD5

Crystal structure of Triazolone derivative bound to the kinase domain of human LCK, (auto-phosphorylated on TYR394)

Summary for 3AD5

• Entry DOI: 10.2210/pdb3ad5/pdb
• Related: 3AD4 3AD6 3LCK
• Descriptor: Proto-oncogene tyrosine-protein kinase LCK, SULFATE ION, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: tyrosine-protein kinase, atp-binding, phosphorylation, signal transduction, kinase, sh2 domain, sh3 domain, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P06239
• Total number of polymer chains: 1
• Total formula weight: 33905.96

Authors

Tsuji, E. (deposition date: 2010-01-14, release date: 2011-01-19, Last modification date: 2024-10-23)

• Primary citation: Ozawa, M.,Ozawa, T.,Tsuji, E.,Okazaki, K.,Takeda, K.; Ab initio fragment molecular orbital study of ligand binding to leukocyte-specific protein tyrosine (LCK) kinase; To be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)