3AA0

Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL

3AA0 の概要

• エントリーDOI: 10.2210/pdb3aa0/pdb
• 関連するPDBエントリー: 1IZN 3AA1 3AA6 3AA7 3AAA 3AAE
• 分子名称: F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, 21mer peptide from Leucine-rich repeat-containing protein 16A, ... (5 entities in total)
• 機能のキーワード: actin capping protein, barbed end regulation, carmil family protein, conformational change, cell motility, actin capping, actin-binding, cytoskeleton, isopeptide bond, leucine-rich repeat, protein binding
• 由来する生物種: Gallus gallus (Chicken); 詳細
• 細胞内の位置: Cytoplasm, myofibril, sarcomere, Z line: P13127; Isoform 1: Cytoplasm, myofibril, sarcomere, Z line . Isoform 2: Cytoplasm, myofibril, sarcomere, I band : P14315; Cytoplasm : Q6EDY6
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 63147.94

構造登録者

Takeda, S.,Minakata, S.,Narita, A.,Kitazawa, M.,Yamakuni, T.,Maeda, Y.,Nitanai, Y. (登録日: 2009-11-11, 公開日: 2010-08-04, 最終更新日: 2023-11-01)

• 主引用文献: Takeda, S.,Minakata, S.,Koike, R.,Kawahata, I.,Narita, A.,Kitazawa, M.,Ota, M.,Yamakuni, T.,Maeda, Y.,Nitanai, Y.; Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition; Plos Biol., 8:e1000416-e1000416, 2010; PubMed: 20625546; DOI: 10.1371/journal.pbio.1000416

実験手法

X-RAY DIFFRACTION (1.7 Å)