3A1L

Crystal Structure of 11,11'-Dichlorochromopyrrolic Acid Bound Cytochrome P450 StaP (CYP245A1)

3A1L の概要

• エントリーDOI: 10.2210/pdb3a1l/pdb
• 関連するPDBエントリー: 2z3t 2z3u
• 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 3,4-bis(7-chloro-1H-indol-3-yl)-1H-pyrrole-2,5-dicarboxylic acid, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, cytochrome p450, monooxygenase, heme-enzyme, heme, iron, metal-binding
• 由来する生物種: Streptomyces sp. TP-A0274
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48333.01

構造登録者

Makino, M.,Sugimoto, H.,Shiro, Y.,Asamizu, S.,Onaka, H.,Nagano, S. (登録日: 2009-04-09, 公開日: 2009-05-12, 最終更新日: 2023-11-01)

• 主引用文献: Wang, Y.,Chen, H.,Makino, M.,Shiro, Y.,Nagano, S.,Asamizu, S.,Onaka, H.,Shaik, S.; Theoretical and experimental studies of the conversion of chromopyrrolic acid to an antitumor derivative by cytochrome P450 StaP: the catalytic role of water molecules; J.Am.Chem.Soc., 131:6748-6762, 2009; PubMed: 19385626; DOI: 10.1021/ja9003365

実験手法