3A06

Crystal structure of DXR from Thermooga maritia, in complex with fosmidomycin and NADPH

3A06 の概要

• エントリーDOI: 10.2210/pdb3a06/pdb
• 分子名称: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, ... (5 entities in total)
• 機能のキーワード: reductoisomerase, mep pathway, isoprene biosynthesis, metal-binding, nadp, oxidoreductase
• 由来する生物種: Thermotoga maritima
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 87168.93

構造登録者

Takenoya, M.,Ohtaki, A.,Noguchi, K.,Sasaki, Y.,Ohsawa, K.,Yohda, M.,Yajima, S. (登録日: 2009-03-02, 公開日: 2010-03-16, 最終更新日: 2024-03-13)

• 主引用文献: Takenoya, M.,Ohtaki, A.,Noguchi, K.,Endo, K.,Sasaki, Y.,Ohsawa, K.,Yajima, S.,Yohda, M.; Crystal structure of 1-deoxy-d-xylulose 5-phosphate reductoisomerase from the hyperthermophile Thermotoga maritima for insights into the coordination of conformational changes and an inhibitor binding; J.Struct.Biol., 170:532-539, 2010; PubMed: 20353826; DOI: 10.1016/j.jsb.2010.03.015

実験手法

X-RAY DIFFRACTION (2 Å)