381D

BINDING OF THE MODIFIED DAUNORUBICIN WP401 ADJACENT TO A T-G BASE PAIR INDUCES THE REVERSE WATSON-CRICK CONFORMATION: CRYSTAL STRUCTURES OF THE WP401-TGGCCG AND WP401-CGG[BR5C]CG COMPLEXES

381D の概要

• エントリーDOI: 10.2210/pdb381d/pdb
• 分子名称: DNA (5'-D(*TP*GP*GP*CP*CP*G)-3'), DNA (5'-D(*TP*GP*(G49)P*CP*CP*G)-3'), 2'-BROMO-4'-EPIDAUNORUBICIN, ... (4 entities in total)
• 機能のキーワード: right handed dna, double helix, complexed with drug, modified, mismatched, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 4877.29

構造登録者

Dutta, R.,Gao, Y.-G.,Priebe, W.,Wang, A.H.-J. (登録日: 1998-02-18, 公開日: 1998-07-13, 最終更新日: 2024-02-21)

• 主引用文献: Dutta, R.,Gao, Y.G.,Priebe, W.,Wang, A.H.; Binding of the modified daunorubicin WP401 adjacent to a T-G base pair induces the reverse Watson-Crick conformation: crystal structures of the WP401-TGGCCG and WP401-CGG[br5C]CG complexes.; Nucleic Acids Res., 26:3001-3005, 1998; PubMed: 9611247; DOI: 10.1093/nar/26.12.3001

実験手法

X-RAY DIFFRACTION (2.1 Å)