2ZHN

Crystal structure of human galectin-9 N-terminal CRD in complex with N-acetyllactosamine trimer (crystal 2)

2ZHN の概要

• エントリーDOI: 10.2210/pdb2zhn/pdb
• 関連するPDBエントリー: 2ZHK 2ZHL 2ZHM
• 分子名称: GALECTIN-9, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, (R)-1-PARA-NITRO-PHENYL-2-AZIDO-ETHANOL, ... (4 entities in total)
• 機能のキーワード: beta sandwich, carbohydrate binding protein, galectin, sugar binding protein
• 由来する生物種: HOMO SAPIENS (human)
• 細胞内の位置: Cytoplasm (By similarity): O00182
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 17680.54

構造登録者

Nagae, M.,Nishi, N.,Murata, T.,Usui, T.,Nakamura, T.,Wakatsuki, S.,Kato, R. (登録日: 2008-02-06, 公開日: 2008-12-30, 最終更新日: 2024-03-13)

• 主引用文献: Nagae, M.,Nishi, N.,Murata, T.,Usui, T.,Nakamura, T.,Wakatsuki, S.,Kato, R.; Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain.; Glycobiology, 19:112-117, 2009; PubMed: 18977853; DOI: 10.1093/glycob/cwn121

実験手法

X-RAY DIFFRACTION (1.3 Å)