2ZFX

Crystal structure of the rat vitamin D receptor ligand binding domain complexed with YR301 and a synthetic peptide containing the NR2 box of DRIP 205

2ZFX の概要

• エントリーDOI: 10.2210/pdb2zfx/pdb
• 分子名称: Vitamin D3 receptor, DRIP 205 NR2 box peptide, (2S)-3-{4-[1-ethyl-1-(4-{[(2R)-2-hydroxy-3,3-dimethylbutyl]oxy}-3-methylphenyl)propyl]-2-methylphenoxy}propane-1,2-diol, ... (4 entities in total)
• 機能のキーワード: hormone/growth factor receptor, dna-binding, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, zinc, zinc-finger, activator, alternative splicing, polymorphism
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Nucleus: P13053 Q15648
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 32085.03

構造登録者

Kakuda, S.,Takimoto-Kamimura, M. (登録日: 2008-01-15, 公開日: 2009-01-20, 最終更新日: 2024-03-13)

• 主引用文献: Kakuda, S.,Okada, K.,Eguchi, H.,Takenouchi, K.,Hakamata, W.,Kurihara, M.,Takimoto-Kamimura, M.; Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301; Acta Crystallogr.,Sect.F, 64:970-973, 2008; PubMed: 18997319; DOI: 10.1107/S1744309108026754

実験手法

X-RAY DIFFRACTION (1.99 Å)