2Z5V
Solution structure of the TIR domain of human MyD88
Summary for 2Z5V
| Entry DOI | 10.2210/pdb2z5v/pdb |
| NMR Information | BMRB: 11078 |
| Descriptor | Myeloid differentiation primary response protein MyD88 (1 entity in total) |
| Functional Keywords | signal transduction innate immunity, cytoplasm, immune response, inflammatory response, immune system |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: Q99836 |
| Total number of polymer chains | 1 |
| Total formula weight | 17387.32 |
| Authors | Ohnishi, H.,Tochio, H.,Hiroaki, H.,Kondo, N.,Kato, Z.,Shirakawa, M. (deposition date: 2007-07-19, release date: 2008-08-05, Last modification date: 2022-03-16) |
| Primary citation | Ohnishi, H.,Tochio, H.,Kato, Z.,Orii, K.E.,Li, A.,Kimura, T.,Hiroaki, H.,Kondo, N.,Shirakawa, M. Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling. Proc.Natl.Acad.Sci.USA, 2009 Cited by PubMed: 19506249DOI: 10.1073/pnas.0812956106 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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