2Z5I

Crystal structure of the head-to-tail junction of tropomyosin

Summary for 2Z5I

Entry DOI	10.2210/pdb2z5i/pdb
Descriptor	General control protein GCN4 and Tropomyosin alpha-1 chain, Tropomyosin alpha-1 chain and General control protein GCN4, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	actin, troponin, tropomyosin, cytoskeleton, cardiomyopathy, contractile protein
Biological source	Saccharomyces cerevisiae (baker's yeast, rabbit) More
Cellular location	Cytoplasm, cytoskeleton: P58772 Nucleus: P03069
Total number of polymer chains	10
Total formula weight	57578.00
Authors	Murakami, K.,Nozawa, K.,Tomii, K.,Kudou, N.,Igarashi, N.,Shirakihara, Y.,Wakatsuki, S.,Stewart, M.,Yasunaga, T.,Wakabayashi, T. (deposition date: 2007-07-12, release date: 2008-04-22, Last modification date: 2024-03-13)
Primary citation	Murakami, K.,Stewart, M.,Nozawa, K.,Tomii, K.,Kudou, N.,Igarashi, N.,Shirakihara, Y.,Wakatsuki, S.,Yasunaga, T.,Wakabayashi, T. Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T Proc.Natl.Acad.Sci.USA, 105:7200-7205, 2008 Cited by PubMed: 18483193 DOI: 10.1073/pnas.0801950105 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation