2Z2M

Cefditoren-Acylated Penicillin-Binding Protein 2X (PBP2X) from Streptococcus pneumoniae

2Z2M の概要

• エントリーDOI: 10.2210/pdb2z2m/pdb
• 関連するPDBエントリー: 2Z2L
• 分子名称: Penicillin-binding protein 2X, SULFATE ION, (2R)-2-[(1R)-1-{[(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-(METHOXYIMINO)ACETYL]AMINO}-2-OXOETHYL]-5-[(Z)-2-(4-METHYL-1,3-THIAZOL-5-YL)VINYL]-3,6-DIHYDRO-2H-1,3-THIAZINE-4-CARBOXYLIC ACID, ... (6 entities in total)
• 機能のキーワード: peptidoglycan synthesis, cell wall, penicillin-binding, antibiotics, cefditoren, biosynthetic protein
• 由来する生物種: Streptococcus pneumoniae; 詳細
• 細胞内の位置: Cell membrane; Single-pass membrane protein: P59676 P59676 P59676
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 149475.32

構造登録者

Yamada, M.,Watanabe, T.,Takeuchi, Y. (登録日: 2007-05-23, 公開日: 2007-09-04, 最終更新日: 2023-11-01)

• 主引用文献: Yamada, M.,Watanabe, T.,Miyara, T.,Baba, N.,Saito, J.,Takeuchi, Y.,Ohsawa, F.; Crystal Structure of Cefditoren Complexed with Streptococcus pneumoniae Penicillin-Binding Protein 2X: Structural Basis for its High Antimicrobial Activity; Antimicrob.Agents Chemother., 51:3902-3907, 2007; PubMed: 17724158; DOI: 10.1128/AAC.00743-07

実験手法

X-RAY DIFFRACTION (2.6 Å)