2YT2
Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK
Summary for 2YT2
| Entry DOI | 10.2210/pdb2yt2/pdb |
| NMR Information | BMRB: 11095 |
| Descriptor | Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor (1 entity in total) |
| Functional Keywords | chimera, snt-2, ptb domain, halk, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Single-pass type I membrane protein: Q9UM73 |
| Total number of polymer chains | 1 |
| Total formula weight | 16953.82 |
| Authors | Li, H.,Koshiba, S.,Tomizawa, T.,Watanabe, S.,Harada, T.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (deposition date: 2007-04-05, release date: 2008-04-08, Last modification date: 2014-02-12) |
| Primary citation | Koshiba, S.,Li, H.,Motoda, Y.,Tomizawa, T.,Kasai, T.,Tochio, N.,Yabuki, T.,Harada, T.,Watanabe, S.,Tanaka, A.,Shirouzu, M.,Kigawa, T.,Yamamoto, T.,Yokoyama, S. Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2 J.Struct.Funct.Genom., 11:125-141, 2010 Cited by PubMed: 20454865DOI: 10.1007/s10969-010-9091-x PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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