2YT2

Solution structure of the chimera of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK

2YT2 の概要

• エントリーDOI: 10.2210/pdb2yt2/pdb
• NMR情報: BMRB: 11095
• 分子名称: Fibroblast growth factor receptor substrate 3 and ALK tyrosine kinase receptor (1 entity in total)
• 機能のキーワード: chimera, snt-2, ptb domain, halk, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: Q9UM73
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 16953.82

構造登録者

Li, H.,Koshiba, S.,Tomizawa, T.,Watanabe, S.,Harada, T.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-04-05, 公開日: 2008-04-08, 最終更新日: 2024-05-01)

• 主引用文献: Koshiba, S.,Li, H.,Motoda, Y.,Tomizawa, T.,Kasai, T.,Tochio, N.,Yabuki, T.,Harada, T.,Watanabe, S.,Tanaka, A.,Shirouzu, M.,Kigawa, T.,Yamamoto, T.,Yokoyama, S.; Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2; J.Struct.Funct.Genom., 11:125-141, 2010; PubMed: 20454865; DOI: 10.1007/s10969-010-9091-x

実験手法

SOLUTION NMR