2YSZ

Solution structure of the chimera of the C-terminal PID domain of Fe65L and the C-terminal tail peptide of APP

2YSZ の概要

• エントリーDOI: 10.2210/pdb2ysz/pdb
• NMR情報: BMRB: 10237
• 分子名称: Amyloid beta A4 precursor protein-binding family B member 2 and Amyloid beta A4 protein (1 entity in total)
• 機能のキーワード: chimera, fe65l, pid domain, amyloid precursor protein, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, protein binding
• 由来する生物種: Mus musculus (mouse)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: P12023
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20007.12

構造登録者

Li, H.,Koshiba, S.,Watanabe, S.,Harada, T.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-04-05, 公開日: 2008-04-08, 最終更新日: 2022-03-16)

• 主引用文献: Li, H.,Koshiba, S.,Hayashi, F.,Tochio, N.,Tomizawa, T.,Kasai, T.,Yabuki, T.,Motoda, Y.,Harada, T.,Watanabe, S.,Inoue, M.,Hayashizaki, Y.,Tanaka, A.,Kigawa, T.,Yokoyama, S.; Structure of the C-terminal phosphotyrosine interaction domain of Fe65L1 complexed with the cytoplasmic tail of amyloid precursor protein reveals a novel peptide binding mode; J.Biol.Chem., 283:27165-27178, 2008; PubMed: 18650440; DOI: 10.1074/jbc.M803892200

実験手法

SOLUTION NMR