2YS5

Solution structure of the complex of the PTB domain of SNT-2 and 19-residue peptide (aa 1571-1589) of hALK

2YS5 の概要

• エントリーDOI: 10.2210/pdb2ys5/pdb
• NMR情報: BMRB: 11094
• 分子名称: Fibroblast growth factor receptor substrate 3, ALK tyrosine kinase receptor (2 entities in total)
• 機能のキーワード: complex, snt-2, ptb domain, halk, structural genomics, nppsfa, national project on protein structural and functional analyses, riken structural genomics/proteomics initiative, rsgi, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Membrane; Lipid-anchor: O43559; Cell membrane; Single-pass type I membrane protein: Q9UM73
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18675.92

構造登録者

Li, H.,Koshiba, S.,Inoue, M.,Kigawa, T.,Yokoyama, S.,RIKEN Structural Genomics/Proteomics Initiative (RSGI) (登録日: 2007-04-03, 公開日: 2008-04-08, 最終更新日: 2014-02-12)

• 主引用文献: Koshiba, S.,Li, H.,Motoda, Y.,Tomizawa, T.,Kasai, T.,Tochio, N.,Yabuki, T.,Harada, T.,Watanabe, S.,Tanaka, A.,Shirouzu, M.,Kigawa, T.,Yamamoto, T.,Yokoyama, S.; Structural basis for the recognition of nucleophosmin-anaplastic lymphoma kinase oncoprotein by the phosphotyrosine binding domain of Suc1-associated neurotrophic factor-induced tyrosine-phosphorylated target-2; J.Struct.Funct.Genom., 11:125-141, 2010; PubMed: 20454865; DOI: 10.1007/s10969-010-9091-x

実験手法

SOLUTION NMR