2YP4

Haemagglutinin of 2004 Human H3N2 Virus in Complex with Human Receptor Analogue LSTc

Summary for 2YP4

• Entry DOI: 10.2210/pdb2yp4/pdb
• Related: 2YP2 2YP3 2YP5 2YP7 2YP8 2YP9 2YPG
• Descriptor: HEMAGGLUTININ, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: viral protein, receptor binding, membrane fusion, glycoprotein
• Biological source: INFLUENZA A VIRUS
• Total number of polymer chains: 1
• Total formula weight: 59788.41

Authors

Xiong, X.,Lin, Y.P.,Wharton, S.A.,Martin, S.R.,Coombs, P.J.,Vachieri, S.G.,Christodoulou, E.,Walker, P.A.,Liu, J.,Skehel, J.J.,Gamblin, S.J.,Hay, A.J.,Daniels, R.S.,McCauley, J.W. (deposition date: 2012-10-29, release date: 2012-11-07, Last modification date: 2020-07-29)

• Primary citation: Lin, Y.P.,Xiong, X.,Wharton, S.A.,Martin, S.R.,Coombs, P.J.,Vachieri, S.G.,Christodoulou, E.,Walker, P.A.,Liu, J.,Skehel, J.J.,Gamblin, S.J.,Hay, A.J.,Daniels, R.S.,Mccauley, J.W.; Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.; Proc.Natl.Acad.Sci.USA, 109:21474-, 2012; PubMed: 23236176; DOI: 10.1073/PNAS.1218841110

Experimental method

X-RAY DIFFRACTION (1.85 Å)