2YBR

Crystal structure of the human derived single chain antibody fragment (scFv) 9004G in complex with Cn2 toxin from the scorpion Centruroides noxius Hoffmann

2YBR の概要

• エントリーDOI: 10.2210/pdb2ybr/pdb
• 関連するPDBエントリー: 1CN2 2YC1
• 分子名称: SINGLE CHAIN ANTIBODY FRAGMENT 9004G, BETA-MAMMAL TOXIN CN2, ... (4 entities in total)
• 機能のキーワード: immune system-toxin complex, scorpion toxin, immune system/toxin
• 由来する生物種: HOMO SAPIENS (HUMAN); 詳細
• 細胞内の位置: Secreted: 2YBR
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 106681.30

構造登録者

Canul-Tec, J.C.,Riano-Umbarila, L.,Rudino-Pinera, E.,Becerril, B.,Possani, L.D.,Torres-Larios, A. (登録日: 2011-03-09, 公開日: 2011-04-13, 最終更新日: 2023-12-20)

• 主引用文献: Canul-Tec, J.C.,Riano-Umbarila, L.,Rudino-Pinera, E.,Becerril, B.,Possani, L.D.,Torres-Larios, A.; Structural Basis of Neutralization of the Major Toxic Component from the Scorpion Centruroides Noxius Hoffmann by a Human-Derived Single Chain Antibody Fragment; J.Biol.Chem., 286:20892-, 2011; PubMed: 21489992; DOI: 10.1074/JBC.M111.238410

実験手法

X-RAY DIFFRACTION (2.55 Å)