2XTB

Crystal Structure of Trypanosoma brucei rhodesiense Adenosine Kinase Complexed with Activator

Summary for 2XTB

Entry DOI	10.2210/pdb2xtb/pdb
Descriptor	ADENOSINE KINASE, 4-[5-(4-PHENOXYPHENYL)-1H-PYRAZOL-3-YL]MORPHOLINE (3 entities in total)
Functional Keywords	transferase
Biological source	TRYPANOSOMA BRUCEI RHODESIENSE
Total number of polymer chains	1
Total formula weight	38452.85
Authors	Kuettel, S.,Greenwald, J.,Kostrewa, D.,Ahmed, S.,Scapozza, L.,Perozzo, R. (deposition date: 2010-10-05, release date: 2011-06-29, Last modification date: 2011-07-13)
Primary citation	Kuettel, S.,Greenwald, J.,Kostrewa, D.,Ahmed, S.,Scapozza, L.,Perozzo, R. Crystal Structures of T. B. Rhodesiense Adenosine Kinase Complexed with Inhibitor and Activator: Implications for Catalysis and Hyperactivation. Plos Negl Trop Dis, 5:E1164-, 2011 Cited by PubMed: 21629723 DOI: 10.1371/JOURNAL.PNTD.0001164 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation