2XRO

Crystal structure of TtgV in complex with its DNA operator

Summary for 2XRO

Related2XRN
DescriptorHTH-TYPE TRANSCRIPTIONAL REGULATOR TTGV, TTGV OPERATOR DNA, OSMIUM ION, ... (4 entities in total)
Functional Keywordsdna-binding protein-dna complex, tetrameric gene regulator, cooperative dna binding, multidrug binding protein, antibiotic resistance, complex (dna-binding protein-dna ), dna-binding protein/dna
Biological sourcePSEUDOMONAS PUTIDA
Total number of polymer chains6
Total molecular weight128969.58
Authors
Lu, D.,Fillet, S.,Meng, C.,Alguel, Y.,Kloppsteck, P.,Bergeron, J.,Krell, T.,Gallegos, M.-T.,Ramos, J.,Zhang, X. (deposition date: 2010-09-17, release date: 2010-12-01, Last modification date: 2011-07-13)
Primary citation
Lu, D.,Fillet, S.,Meng, C.,Alguel, Y.,Kloppsteck, P.,Bergeron, J.,Krell, T.,Gallegos, M.T.,Ramos, J.,Zhang, X.
Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators.
Genes Dev., 24:2556-, 2010
PubMed: 21078819 (PDB entries with the same primary citation)
DOI: 10.1101/GAD.603510
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.4 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.279260.5%5.9%4.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution