2XRD

Structure of the N-terminal four domains of the complement regulator Rat Crry

2XRD の概要

• エントリーDOI: 10.2210/pdb2xrd/pdb
• 関連するPDBエントリー: 1NTJ 2XRB
• 分子名称: COMPLEMENT REGULATORY PROTEIN CRRY (1 entity in total)
• 機能のキーワード: immune system, extracellular protein, sushi (ccp/scr) domains
• 由来する生物種: RATTUS NORVEGICUS (NORWAY RAT)
• 細胞内の位置: Membrane; Single-pass type I membrane protein: Q63135
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31925.39

構造登録者

Leath, K.J.,Roversi, P.,Johnson, S.,Morgan, B.P.,Lea, S.M. (登録日: 2010-09-14, 公開日: 2011-06-22, 最終更新日: 2024-11-13)

主引用文献

Roversi, P.,Johnson, S.,Caesar, J.J.E.,Mclean, F.,Leath, K.J.,Tsiftsoglou, S.A.,Morgan, B.P.,Harris, C.L.,Sim, R.B.,Lea, S.M.
Structures of the Rat Complement Regulator Crry.
Acta Crystallogr.,Sect.F, 67:739-, 2011

PubMed Abstract: Complement receptor 1-related protein Y (CrrY) is an important cell-surface regulator of complement that is unique to rodent species. The structure of rat CrrY domains 1-4 has been determined in two distinct crystal forms and reveals a 70° bend between domains 3 and 4. Comparisons of this structure with those of other complement regulators suggests that rearrangement of this interface may occur on forming the regulatory complex with C3b.

PubMed: 21795784
DOI: 10.1107/S1744309111016551

実験手法

X-RAY DIFFRACTION (3.5 Å)