2XG5

E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 5d

Summary for 2XG5

Entry DOI	10.2210/pdb2xg5/pdb
Related	1N0L 1PDK 1QPP 1QPX 2J2Z 2WMP 2XG4 3DPA
Descriptor	CHAPERONE PROTEIN PAPD, PAP FIMBRIAL MINOR PILIN PROTEIN, GLYCEROL, ... (8 entities in total)
Functional Keywords	chaperone, chaperone-surface active protein complex
Biological source	ESCHERICHIA COLI More
Cellular location	Periplasm: P15319 Secreted: P07111
Total number of polymer chains	2
Total formula weight	45039.85
Authors	Remaut, H.,Phan, G.,Buelens, F.,Chorell, E.,Pinkner, J.S.,Edvinsson, S.,Almqvist, F.,Hultgren, S.J.,Waksman, G. (deposition date: 2010-05-30, release date: 2010-07-14, Last modification date: 2023-12-20)
Primary citation	Chorell, E.,Pinkner, J.S.,Phan, G.,Edvinsson, S.,Buelens, F.,Remaut, H.,Waksman, G.,Hultgren, S.J.,Almqvist, F. Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity. J.Med.Chem., 53:5690-, 2010 Cited by PubMed: 20586493 DOI: 10.1021/JM100470T PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation