2XE2

Molecular insights into clinically isolated OmpC20 mutants and their role in multi-drug resistance

Replaces:  2IXW

Summary for 2XE2

• Entry DOI: 10.2210/pdb2xe2/pdb
• Related: 2XE1 2XE3
• Descriptor: OUTER MEMBRANE PORIN C, N-OCTYL-2-HYDROXYETHYL SULFOXIDE (3 entities in total)
• Functional Keywords: cell membrane, transport protein, ion transport
• Biological source: ESCHERICHIA COLI
• Cellular location: Cell outer membrane; Multi-pass membrane protein (By similarity): Q9K597
• Total number of polymer chains: 3
• Total formula weight: 115465.64

Authors

Bamford, V.A.,Naismith, J.H. (deposition date: 2010-05-10, release date: 2010-05-19, Last modification date: 2023-12-20)

• Primary citation: Lou, H.,Chen, M.,Black, S.S.,Bushell, S.R.,Ceccarelli, M.,Mach, T.,Beis, K.,Low, A.S.,Bamford, V.A.,Booth, I.R.,Bayley, H.,Naismith, J.H.; Altered Antibiotic Transport in Ompc Mutants Isolated from a Series of Clinical Strains of Multi-Drug Resistant E. Coli.; Plos One, 6:25825-, 2011; PubMed: 22053181; DOI: 10.1371/JOURNAL.PONE.0025825

Experimental method

X-RAY DIFFRACTION (2.5 Å)