2XCW

Crystal structure of the D52N variant of cytosolic 5'-nucleotidase II in complex with inosine monophosphate and ATP

Summary for 2XCW

Entry DOI	10.2210/pdb2xcw/pdb
Related	2J2C 2JC9 2JCM 2XCV 2XCX 2XJB 2XJC 2XJD 2XJE 2XJF
Descriptor	CYTOSOLIC PURINE 5'-NUCLEOTIDASE, ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... (6 entities in total)
Functional Keywords	cn-ii, gmp-imp specific nucleotidase, high km 5-prime nucleotidase, hydrolase, metal-binding, nt5c2, nucleotide metabolism, nucleotide-binding
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P49902
Total number of polymer chains	1
Total formula weight	65413.31
Authors	Wallden, K.,Nordlund, P. (deposition date: 2010-04-26, release date: 2011-03-16, Last modification date: 2023-12-20)
Primary citation	Wallden, K.,Nordlund, P. Structural Basis for the Allosteric Regulation and Substrate Recognition of Human Cytosolic 5'-Nucleotidase II J.Mol.Biol., 408:684-, 2011 Cited by PubMed: 21396942 DOI: 10.1016/J.JMB.2011.02.059 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation