Summary for 2XCF
| Descriptor | NS3 PROTEASE, NS4A, ZINC ION, ... (6 entities in total) |
|---|---|
| Functional Keywords | protease, boronate inhibitor, viral reproduction, hydrolase |
| Biological source | HEPATITIS C VIRUS |
| Total number of polymer chains | 4 |
| Total molecular weight | 47604.93 |
| Authors | Li, X.,Zhang, Y.-K.,Liu, Y.,Ding, C.Z.,Li, Q.,Zhou, Y.,Plattner, J.J.,Baker, S.J.,Qian, X.,Fan, D.,Liao, L.,Ni, Z.-J.,White, G.V.,Mordaunt, J.E.,Lazarides, L.X.,Slater, M.J.,Jarvest, R.L.,Thommes, P.,Ellis, M.,Edge, C.M.,Hubbard, J.A.,Nassau, P.,McDowell, B.,Skarzynski, T.J.,Rowland, P.,Somers, D.O.,Kazmierski, W.M.,Grimes, R.M.,Wright, L.L.,Smith, G.K.,Zou, W.,Wright, J.,Pennicott, L.E. (deposition date: 2010-04-22, release date: 2010-06-02, Last modification date: 2019-02-06) |
| Primary citation | Li, X.,Zhang, Y.-K.,Liu, Y.,Ding, C.Z.,Li, Q.,Zhou, Y.,Plattner, J.J.,Baker, S.J.,Qian, X.,Fan, D.,Liao, L.,Ni, Z.-J.,White, G.V.,Mordaunt, J.E.,Lazarides, L.X.,Slater, M.J.,Jarvest, R.L.,Edge, C.M.,Hubbard, J.A.,Nassau, P.,Mcdowell, B.,Skarzynski, T.J.,Thommes, P.,Ellis, M.,Rowland, P.,Somers, D.O.,Kazmierski, W.M.,Grimes, R.M.,Wright, L.L.,Smith, G.K.,Zou, W.,Wright, J.,Pennicott, L.E. Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease. Bioorg.Med.Chem.Lett., 20:3550-, 2010 PubMed: 20493689 (PDB entries with the same primary citation) DOI: 10.1016/J.BMCL.2010.04.129  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.48 Å) |
